Interactomics Course: Basics, Applications & Technologies | IIT Bombay
Course Details
| Exam Registration | 104 |
|---|---|
| Course Status | Ongoing |
| Course Type | Elective |
| Language | English |
| Duration | 12 weeks |
| Categories | Biological Sciences & Bioengineering, Biosciences |
| Credit Points | 3 |
| Level | Undergraduate/Postgraduate |
| Start Date | 19 Jan 2026 |
| End Date | 10 Apr 2026 |
| Enrollment Ends | 02 Feb 2026 |
| Exam Registration Ends | 20 Feb 2026 |
| Exam Date | 24 Apr 2026 IST |
| NCrF Level | 4.5 — 8.0 |
Interactomics: Decoding the Molecular Conversations of Life
In the intricate world of a living cell, proteins are not solitary actors. They form a dynamic, interacting network—constantly communicating, binding, and triggering cascades of events that dictate health and disease. Understanding this complex social network of biomolecules is the realm of Interactomics. This field is revolutionizing our approach to biology, offering unprecedented insights into disease mechanisms and paving the way for next-generation diagnostics and therapeutics.
What is Interactomics?
Interactomics is the large-scale study of interactions between biological molecules, with a primary focus on proteins. It goes beyond simply cataloging proteins to mapping the intricate web of their relationships—including protein-protein, protein-DNA, protein-RNA, and protein-small molecule interactions. By deciphering these 'molecular conversations,' scientists can uncover the fundamental mechanisms of cellular processes and identify critical hubs in disease pathways.
About the Interactomics Course
This comprehensive 12-week course, designed and instructed by Prof. Sanjeeva Srivastava from the Indian Institute of Technology Bombay (IIT Bombay), provides a deep dive into the world of interactomics. It bridges the gap between cutting-edge research and practical application, making it an invaluable resource for students and researchers alike.
Learn from a Global Leader: Prof. Sanjeeva Srivastava
Prof. Sanjeeva Srivastava heads the Proteomics Laboratory at IIT Bombay. With a Ph.D. from the University of Alberta and post-doctoral training at Harvard Medical School, he is a distinguished figure in global proteomics. His research focuses on biomarker discovery and mapping protein interaction networks in complex diseases like gliomas and malaria.
An active contributor to the global science community, Prof. Srivastava serves on the executive councils of the Human Proteome Organization (HUPO) and the Proteomics Society, India (PSI). He is a pioneer in proteomics education, having developed popular MOOC courses on mass spectrometry and interactomics, and created the first-ever proteomics documentaries.
Who Should Enroll?
This course is ideally suited for:
- Undergraduate and Postgraduate students in Biology, Biotechnology, or related fields.
- BE/B.Tech students in Biotechnology.
- B.Sc. students with a science background.
- Researchers and faculty seeking to update their knowledge on high-throughput interaction technologies.
- Professionals in the biotech and pharmaceutical industries.
Industry Support: This course's relevance is underscored by support from leading industry players like GE Healthcare, Pall Life Sciences, Thermo Fisher Scientific, and Illumina.
Detailed 12-Week Course Curriculum
The course is meticulously structured to take you from foundational concepts to advanced applications and data analysis.
| Week | Key Topics Covered |
|---|---|
| Weeks 1-3 | Introduction to Proteomics & Interactomics. Deep dive into Protein Microarray technologies like NAPPA, focusing on biomarker discovery and immune response profiling. |
| Weeks 4-6 | Applications in disease research (e.g., Malaria, Cancer). Hands-on demos of bioprinting and data acquisition. Introduction to Reverse Phase Protein Arrays (RPPA). |
| Weeks 7-9 | Mastering Label-Free Technologies: Principles and hands-on applications of Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI) for studying protein-protein and protein-small molecule interactions. |
| Weeks 10-12 | Integration with Mass Spectrometry and Next-Generation Sequencing (NGS) platforms (Ion Torrent, Illumina). Focus on bioinformatics, statistical analysis, pathway enrichment, and multi-omics data integration for systems biology. |
Key Technologies and Skills You Will Master
- High-Throughput Screening: Protein microarrays (NAPPA, RPPA).
- Label-Free Interaction Analysis: Surface Plasmon Resonance (SPR) and Bio-Layer Interferometry (BLI).
- Omics Integration: Next-Generation Sequencing (NGS) and Mass Spectrometry-coupled interactomics.
- Data Science for Biology: Bioinformatics pipelines, statistical analysis, and network/pathway enrichment using public databases.
- Translational Applications: Biomarker discovery, drug target identification, and understanding host-pathogen interactions.
Why This Course is Essential
As biology becomes increasingly data-driven, the ability to study biomolecular interactions at scale is a critical skill. This course offers a unique blend of theoretical knowledge and insights into practical, industry-relevant technologies. It prepares you to contribute to advancing fields like personalized medicine, drug discovery, and systems biology by providing a comprehensive toolkit to explore the interactome.
Embark on this journey to map the molecular universe within us. Enroll in the Interactomics course and learn from one of the field's leading experts to unlock the secrets of cellular communication and its applications in improving human health.
Ready to decode the network of life? Explore the course and the pioneering work of Prof. Srivastava's lab to begin your journey into interactomics.
Enroll Now →